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Regularized sequence-context mutational trees capture variation in mutation rates across the human genome.

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Germline mutation is the mechanism by which genetic variation in a population is created. Inferences derived from mutation rate models are fundamental to many population genetics methods. Previous models have demonstrated that nucleotides flanking polymorphic sites-the local sequence context-explain variation in the probability that a site is polymorphic. https://www.dunebarcelona.com/product-category/parts/
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